When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism

IMAGE: The transcription factors IKAROS and AIOLOS (named after Greek mythology characters) regulate lymphocyte development. According to Greek mythology, Ikaros had wings that were made of feathers and wax; one day,… view more  Credit: Department of Pediatrics and Developmental Biology,TMDU Tokyo, Japan – Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune…

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First 3D simulation of rat’s complete whisker system acts as a tactile ‘camera’

Northwestern University engineers have developed the first full, three-dimensional (3D), dynamic simulation of a rat’s complete whisker system, offering rare, realistic insight into how rats obtain tactile information. Called WHISKiT, the new model incorporates 60 individual whiskers, which are each anatomically, spatially and geometrically correct. The technology could help researchers predict how whiskers activate different…

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Study identifies monoclonal antibodies that may neutralize many norovirus variants

IMAGE: James Crowe Jr., MD, director of the Vanderbilt Vaccine Center view more  Credit: Vanderbilt University Medical Center Researchers at Vanderbilt University Medical Center (VUMC) and the Baylor College of Medicine in Houston, Texas, have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract. Each…

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New Sinai Health research finds common denominator linking all cancers

IMAGE: Lunenfeld-Tanenbaum Research Institute scientists Joel Pearson, left, and Rod Bremner, right, divided all cancers into two groups, based on the presence or absence of a protein called the Yes-associated protein,… view more  Credit: Sinai Health All cancers fall into just two categories, according to new research from scientists at Sinai Health, in findings that could…

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How a butterfly tree becomes a web

IMAGE: Gene flow between species is indicated with dotted blue lines. Below: Butterflies of two different species (Heliconius cydno chioneus and H. melpomene rosina) mating on a Psychotria poeppigiana flower in… view more  Credit: Image by Krzysztof Kozak and Jorge Aleman. Photo credits: Luca Livraghi, Michel Cast. Evolution is often portrayed as a tree, with new…

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From birth control to mammograms, many women missed out on preventive care for all of 2020

The COVID-19 pandemic knocked many women off schedule for important health appointments, a new study finds, and many didn’t get back on schedule even after clinics reopened. The effect may have been greatest in areas where such care is already likely falling behind experts’ recommendations. The study, by health care researchers in the University of…

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