WHAT: A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a rare neurological disorder that develops in infancy and leads to near absent levels of certain brain chemicals, serotonin and dopamine, that are…
DetailsIMAGE: Gene flow between species is indicated with dotted blue lines. Below: Butterflies of two different species (Heliconius cydno chioneus and H. melpomene rosina) mating on a Psychotria poeppigiana flower in… view more Credit: Image by Krzysztof Kozak and Jorge Aleman. Photo credits: Luca Livraghi, Michel Cast. Evolution is often portrayed as a tree, with new…
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A UC San Francisco study has found that the antibiotic azithromycin was no more effective than a placebo in preventing symptoms of COVID-19 among non-hospitalized patients, and may increase their chance of hospitalization, despite widespread prescription of the antibiotic for the disease. “These findings do not support the routine use of azithromycin for outpatient SARS-CoV-2…
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ATLANTA–An oral prodrug developed by a team of scientists led by Binghe Wang, Regents’ Professor of Chemistry at Georgia State University, delivers carbon monoxide to protect against acute kidney injury, according to a new paper published in Chemical Science. Although carbon monoxide (CO) gas is toxic in large doses, scientists have discovered it can have…
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The COVID-19 pandemic knocked many women off schedule for important health appointments, a new study finds, and many didn’t get back on schedule even after clinics reopened. The effect may have been greatest in areas where such care is already likely falling behind experts’ recommendations. The study, by health care researchers in the University of…
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Vaccine negativity and reluctance didn’t just emerge during the COVID-19 pandemic. In a recent study published in the Disaster Medicine and Public Health Preparedness journal, authors from Loyola University Maryland and Johns Hopkins Bloomberg School of Public Health explored the appearance of negative dominance – a concept in which negative messages outweigh positive, solution-oriented messages…
DetailsIMAGE: H3K9 methylation levels in the cerebellum were lower in the Suv39h2-deficient mice than in control mice controls. view more Credit: RIKEN New research from the RIKEN Center for Brain Science (CBS) in Japan shows that a deficit in histone methylation could lead to the development of autism spectrum disorders (ASD). A human variant of the…
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A new method developed by Institute for Systems Biology (ISB) and University of California, Riverside provides new insights into cancer biology by allowing researchers to show how fatty acids are absorbed by single cells. Fatty acids, along with glucose and amino acids, are a major energy source for cellular growth and proliferation, and abnormal fatty…
DetailsIMAGE: A vaccination in Central Java, Indonesia view more Credit: Fadil Fauzi New research published in Nature Medicine reveals willingness to get a COVID-19 vaccine was considerably higher in developing countries (80% of respondents) than in the United States (65%) and Russia (30%). The study provides one of the first insights into vaccine acceptance and hesitancy…
DetailsIMAGE: Figure depicts SARS-CoV-2 spreading through blood vessels (green) to infect pericytes (red), which amplify infection and can spread infection to other cell types in the brain. view more Credit: UC San Diego Health Sciences Researchers at University of California San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem…
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