Use of a homozygous G608G progeria mouse model for degenerative joint diseases research

BOSTON – Hutchinson-Gilford Progeria Syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease and a potential treatment or cure. In a study published today in the journal Proceedings of the National Academies of Science, researchers…

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Neural logic

Everything we do comes down to a series of neural signals that translate into physical behaviors. We receive information through our senses, sensory neurons convert this information into electrical and chemical signals that are processed by other neurons in our brains and ultimately, motor neurons fire muscles that move our limbs. But how these signals…

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Effects of antioxidant rich Indo-Mediterranean foods on pre-heart failure

The role of diets in the pathogenesis of cardiac dysfunction is controversial. However, it is well known that Western diet causes oxidative stress and has pro-inflammatory effects, whereas Mediterranean style diets are anti-inflammatory. Recently, cohort studies and case control studies, have demonstrated that western style diets rich in sugar and physical inactivity with obesity are…

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Leading the way in innovative research for COVID-19 patients

CLEVELAND – As the COVID-19 pandemic continues, there is great interest in studying treatment and prevention approaches for the disease. Cleveland Clinic is participating in a number of research projects related to COVID-19. As an international leader in biomedical research, Cleveland Clinic has formed a multidisciplinary clinical trials committee to evaluate therapies for mild to…

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Study finds rising rate of mental health visits among youth to emergency departments

(COLUMBUS, Ohio) – While the number of pediatric emergency department (ED) visits across the nation has remained stable over the last 10 years, visits for mental health disorders have risen 60% and the rate of visits for deliberate self-harm have increased 329%. In a study published today in Pediatrics, Nationwide Children’s Hospital researchers looked at…

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‘Bug Zapper’ uses UV-C light to enable the sterilization and reuse of N95 masks

Right around the time in mid-March when Lehigh University moved to remote learning and researchers began to shut down on-campus labs, Nelson Tansu, the Daniel E. ’39 and Patricia M. Smith Endowed Chair Professor in the department of electrical and computer engineering (ECE), received an email from Dr. Christopher Roscher, an anesthesiologist at St. Luke’s…

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