Herpes virus decoded

Until now, scientists had assumed that there are about 80 so-called open reading frames (ORFs) in the genome of herpes simplex virus 1 (HSV-1). These are the locations in the genome where the information in the DNA is read and translated into proteins. It is now clear that there are a lot more – namely…

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MD Anderson and Ipsen advance new therapy with potential benefit for underserved patients with lung and ovarian cancers

HOUSTON — In a first-time disclosure of IPN60090, a small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), researchers from The University of Texas MD Anderson Cancer Center’s Therapeutics Discovery division and Ipsen Biopharmaceuticals reported the preclinical discovery and early-stage clinical development of this novel drug. IPN60090, now under investigation in a Phase I trial, may…

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