Host tissue T cells may have an unexpected role in graft-versus-host disease

Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor’s healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer. While this therapy can be life-saving, a major complication is the development of graft-versus-host disease (GVHD), which causes significant morbidity and can be fatal. Before allogenic…

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Look beyond opioids to solve national substance use epidemic, study suggests

Overcoming the nation’s opioid epidemic will require clinicians to look beyond opioids, new research from Oregon Health & Science University suggests. The study reveals that among patients who participated in an in-hospital addiction medicine intervention at OHSU, three-quarters came into the hospital using more than one substance. Overall, participants used fewer substances in the months…

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Scientists listed the main approaches to the treatment of coronavirus

Researchers from Sechenov University together with Russian and Iranian colleagues described currently known approaches to the treatment of SARS-CoV-2 infection. In the paper published in Journal of Molecular Medicine, they wrote about how different groups of drugs worked and how promising each approach was. SARS-CoV-2 – a coronavirus that caused the pandemic in early 2020…

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Thomas Jefferson University awarded $508,000 by the Commonwealth to support CoraVax™

(Philadelphia, PA, USA) The Commonwealth of Pennsylvania has announced grants totaling $10M to 23 entities to develop effective COVID-19 vaccines, treatments and therapies. The selection from the 70+ applicants was a competitive process that required matched funding in order to be considered. In addition to Governor Wolf, Secretaries Dr. Rachel Levine (Health) and Mr. Dennis…

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Experiment contradicts assumptions about sleep loss and criminal interrogations

DARIEN, IL – An experimental study suggests that sleep restriction may hinder information disclosure during criminal interviews, contradicting widespread assumptions about the effectiveness of sleep deprivation as an interrogation tool. Preliminary results show that even mildly sleep-restricted participants provided around 7% less information during their initial disclosure. Sleep-restricted individuals also reported less overall motivation to…

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Waiting for Godot Metaphor

The “Waiting for Godot Metaphor” for the COVID-19 response is carried forward and in an “Epilogue” a series of questions that have no clear answer are used to guide the discussion. The lead question examines the justification of the WHO Declaration of a Pandemic back in March in light of the heightened socio-economic damage that…

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C.D.C.’s ‘Clarification’ on Coronavirus Testing Offers More Confusion

WASHINGTON — The director of the Centers for Disease Control and Prevention, seeking to clarify recommendations on coronavirus testing that incited an uproar, said that “testing may be considered for all close contacts of confirmed or probable Covid-19 patients.” But his clarification may have further confused the issue. The statement by the director, Dr. Robert…

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