EULAR: Early and intensive treatment of rheumatoid arthritis reduces fatigue

Kilchberg/Switzerland: Disease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian study (1) has now concluded that early intensive treatment combining methotrexate with a bridging scheme of prednisone can reduce the onerous fatigue – this also applies to patients at low risk of a severe course. The…

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C-Path’s Transplant Therapeutics Consortium Letter of Intent accepted by FDA

TUCSON, Ariz., June 17, 2020 — Critical Path Institute (C-Path) announced today that its Transplant Therapeutics Consortium (TTC) has received a positive response to its Letter of Intent (LOI) from the U.S. Food and Drug Administration (FDA) detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation…

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During the COVID-19 outbreak in China, marked emission reductions, but unexpected air pollution

Using a combination of satellite and ground-based observations to study air pollution changes in China during COVID-19 lockdowns, researchers report up to 90% reductions of certain emissions, but also an unexpected increase in particulate matter pollution. The results will inform efforts to regulate precursor gases from all possible sectors when developing an emission control strategy.…

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UConn researchers overcome a vexing problem in vaccine research

Researchers at UConn’s Center of Excellence in Vaccine Research (CEVR) have made a breakthrough in vaccine development for a common and difficult to treat pneumonia-causing pathogen. Their research was recently published in the Nature Partner Journal – Vaccines. For Mycoplasma pneumoniae, vaccine development has been stalled since the 1960s due to a phenomena called vaccine-enhanced…

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