Tethering together type 2 diabetes drugs increases efficacy of combination therapy

DURHAM, N.C. – Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered. The combination molecule is formed by an elastin-like polypeptide (ELP) linker that forms a gel-like depot when injected under the…

Details

New study explores symptomatology, quality of life before and after labiaplasty

August 26, 2020 – For patients with elongated labia, vague terms like “vaginal rejuvenation” and “designer vagina” can undermine the seriousness of the condition, which includes a variety of functional concerns. Often attributed to congenital causes, exogenous hormones, chronic irritation, childbirth, aging and external physical causes, women at nearly every age, from birth to later…

Details

Researchers pursue ‘hidden pathology’ to explain fatigue in multiple sclerosis

Up to 60 percent of patients with multiple sclerosis (MS) report that fatigue is the disease’s most debilitating symptom. And yet, fatigue remains one of MS’s mysteries — despite its prevalence and significance, the root cause of the symptom remains unclear. In a study published in Neurology Neuroimmunology & Neuroinflammation, investigators from Brigham and Women’s…

Details

McDonald’s Investigating Whether Former C.E.O. Covered Up Others’ Misconduct

McDonald’s said on Tuesday that its investigation into misconduct claims within the company now included whether its former chief executive, Steve Easterbrook, may have covered up inappropriate actions by other executives during his tenure. The company also said it was examining the actions of its human resources department. “The board will follow the facts wherever…

Details

Covid-19 Live Updates: C.D.C. Changes Testing Guidance to Exclude People Without Symptoms, Worrying Experts

Here’s what you need to know: ImageMedical staff taking a sample at a coronavirus testing site in Houston last week.Credit…Go Nakamura for The New York Times The C.D.C. changes testing guidelines to exclude those exposed to virus who don’t exhibit symptoms. The Centers for Disease Control and Prevention quietly modified its coronavirus testing guidelines this…

Details