When developing vaccines against COVID-19, ‘fast is slow, and slow is fast’

Bypassing clinical trials for a potential SARS-CoV-2 vaccine would be “catastrophic,” says Science Advances deputy editor Douglas Green in this Editorial. Instead, it’s vital to take time to ensure any vaccine candidate’s safety and investigate potential adverse effects, he says. A vaccine able to trigger strong neutralizing antibody responses in clinical tests will still not…

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Large-scale analysis of protein arginine methylation by mass spectrometry

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs). PRMTs have been gaining increasing attention in the scientific landscape due their role in several essential physiological processes and implication in various diseases, including…

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Introducing TVT connect

NEW YORK – May 22, 2020 – The Cardiovascular Research Foundation (CRF) has announced that TVT Connect, the Structural Heart Summit, will take place online June 18-28, 2020. TVT Connect features expertly developed series, late-breaking clinical science, challenging cases, industry-sponsored sessions, and connection to a community of thought leaders from across the globe. “We transformed…

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Anti-obesity medications mitigate weight regain in RYGB surgery patients

SILVER SPRING, Md.–Researchers have discovered that anti-obesity medications such as phentermine and topiramate, used individually or in combination, can significantly reduce weight regain in patients after Roux-en-Y gastric bypass surgery, according to a retrospective study published online in Obesity, the flagship journal of The Obesity Society. “Our study provides evidence that medications can help, especially…

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FCC awards Children’s National $928K for regional pediatric telehealth consortium

WASHINGTON – (May 21,2020) — Children’s National Hospital is establishing a regional pediatric telehealth consortium in response to coronavirus with $928,000 in funding awarded by the Federal Communications Commission’s Wireline Competition Bureau. The funding, which is part of the FCC’s COVID-19 Telehealth Program, enables the nationally-ranked pediatric hospital to expand its telehealth platform to support…

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Platinum-based chemo may improve survival for some metastatic pancreatic cancer patients

Bottom Line: Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research Authors: The senior author was…

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