Doctors may be able to predict their patients’ risks of fatal coronary heart disease more accurately by taking into account the number of adverse social factors affecting them, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The researchers, whose findings appear Dec. 3 in Circulation, analyzed data from the…
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The SARS-CoV-2 virus may enter and replicate in human cells by exploiting newly-identified sequences within cell receptors, according to work from two teams of scientists. The findings from both groups paint a more complete portrait of the various cellular processes that SARS-CoV-2 targets to not only enter cells, but to then multiply and spread. The…
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Chimeric Antigen Receptor T-cell therapy–CAR T–has revolutionized leukemia treatment. Unfortunately, the therapy has not been effective for treating solid tumors including childhood cancers such as neuroblastoma. Preclinical studies using certain CAR T against neuroblastoma revealed toxic effects. Now, a group of scientists at Children’s Hospital Los Angeles have developed a modified version of CAR T…
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The year 2021 marks the 100th anniversary of a fundamental discovery that’s taught in every biochemistry textbook. In 1921, German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely inefficient manner: rather than “burn” it using oxygen, cancer cells do what yeast do — they ferment it. This oxygen-independent…
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A new study exploring the impact of repeated sleep loss during a simulated working week has found that consuming caffeinated coffee during the day helps to minimize reductions in attention and cognitive function, compared to decaffeinated coffee1. While this effect occurred in the first three-to-four days of restricted sleep, by the fifth and final day,…
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PHILADELPHIA–Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in JNCI Cancer Spectrum shows. Past reports have established an increased risk of severe disease and death for sick or hospitalized cancer patients with COVID-19 compared…
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A recent study published in Acta Obstetricia et Gynecologica Scandinavica found that questions typically asked to new mothers to screen for depression after giving birth can also help to detect depressive symptoms and other mental disorders during early pregnancy. The questions are part of what’s called the Edinburgh Postnatal Depression Scale. In the study of…
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The US prevalence of the autoimmune disease lupus is 72.8 cases per 100,000 individuals, according to an analysis of population-based registries. The analysis, which is published in Arthritis & Rheumatology, found that the rate is 9 times higher for females than males (128.7 vs. 14.6 per 100,000), and it’s highest among American Indians/Alaska Natives and…
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Where people die can affect the quality of their deaths and the end-of-life care that they receive. A study published in the Journal of the American Geriatrics Society found that satisfaction with end-of-life care was rated highest when individuals died at home. Analyzing data from the National Health and Aging Trends Study of community-dwelling Medicare…
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Pharmacists play an important role in managing medication-based therapies for older community-dwelling patients, according to a study published in the British Journal of Clinical Pharmacology. In the study of patients aged 65 years and older who came to a pharmacist-led outpatient clinic at a general hospital in Beijing, China between 2016 and 2018, pharmacists were…
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