Bigger may not always be better: Density governs receptor activation on immune cells

IMAGE: CD40 receptor clustering driven by CD40 ligand or anti-CD40 antibody, 341G2 with the human IgG2 (h2) isotype. Jurkat cells expressing full length hCD40-green fluorescent protein (GFP), were treated with 10… view more  Credit: University of Southampton Scientists from within the Antibody and Vaccine Group at the University of Southampton have gained novel insights into how…

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Application of postbiotics science and technology

Postbiotics: Science, Technology, and Applications explains essential and practical knowledge about postbiotics. Chapters cover the definition and classification of postbiotics, principal methods for preparing them, information about the main post biotic constituents and their biological activities and their clinical health benefits. The authors also familiarize the reader with potential applications of postbiotics in the food…

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Performance-enhancing substance use: A link to criminal offending

Toronto, ON – Despite research showing associations between anabolic steroid use and criminal offending, the possibility of a similar association between legal performance-enhancing substance use, such as creatine, and criminal offending remained unknown. A new study published online in the journal Drug and Alcohol Dependence now shows that both forms of performance-enhancing substance use is…

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Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants

New SARS-CoV-2 variants are spreading rapidly, and there are fears that current COVID-19 vaccines won’t protect against them. The latest in a series of structural studies of the SARS-CoV-2 variants’ “spike” protein, led by Bing Chen, PhD, at Boston Children’s Hospital, reveals new properties of the Alpha (formerly U.K.) and Beta (formerly South Africa) variants.…

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