Neonatal meningitis: the immaturity of microbiota and epithelial barriers implicated

IMAGE: Choroid plexus of mouse neonates. Blue: cell nuclei, green: phalloidin-actin, red: fluorochrome. view more  Credit: Biology of Infection Unit, Institut Pasteur Meningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population. Group B…

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COVID-19 pandemic linked to reduced access to gender-affirming care in 76 countries

A survey offered to transgender and nonbinary people across six continents and in thirteen languages shows that during the first months of the COVID-19 pandemic, many faced reduced access to gender-affirming resources, and this reduction was linked to poorer mental health. Brooke Jarrett of the Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, and…

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Dying cells protect their neighbors to maintain tissue integrity

IMAGE: Artistic rendering of dying cells protecting their neighbors to maintain tissue integrity. Holes in epithelium created by uncoordinated cell death are shown in purple. view more  Credit: © Institut Pasteur / Le?o Valon et Romain Levayer To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form and connectivity. The…

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With $3M grant, UArizona-led center to advance at-home health care technology

IMAGE: multi-institution team led by University of Arizona electrical and computer engineering professor Janet Roveda is building a future in which wearable devices will allow clinicians to gather patient data remotely… view more  Credit: University of Arizona The last two decades have seen an uptick in people choosing to monitor their health using wearable technologies such…

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Normal brain growth curves for children developed childhood brain disorders, infections and injuries

IMAGE: Using brain scans from children across the United States, researchers developed normalized growth charts for how healthy brains should grow during the first 18 years of life. Image: view more  Credit: humonia/Image compilation: College of Engineering In the United States, nearly every pediatric doctor’s visit begins with three measurements: weight, height and head circumference. Compared…

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For pediatric patients with Crohn’s disease, factors associated with statural growth differ by sex

Growth impairment, a common complication of Crohn’s disease in children, occurs more often in males than females, but the reasons are unclear. Now, a physician-scientist from Weill Cornell Medicine and NewYork-Presbyterian and colleagues at eight other centers have found that factors associated with statural growth differ by sex. Their recent publication, identified as the “Editor’s…

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