ACR releases reproductive health guideline for patients with rheumatic diseases

ATLANTA – Today, the American College of Rheumatology (ACR) published the 2020 Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases. This is the first, evidence-based, clinical practice guideline related to the management of reproductive health issues for all patients with rheumatic diseases. With 131 recommendations, the guideline offers general precepts that…

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Too much of a good thing may lead to too much of a liver as well

All life is challenged by oxidants — reactive molecules or compounds that remove electrons from other molecules — often with adverse effect, commonly referred to as oxidative stress. Consequently, all organisms have evolved specialized antioxidant defenses. In humans and other multicellular animals, that defense depends upon a protein called NRF2 and its inhibitor, KEAP1. In…

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‘CRISPR: A Screener’s Guide’ headlines the March edition of SLAS Discovery

Oak Brook, IL – The March edition of SLAS Discovery features the cover article, “CRISPR: A Screener’s Guide,” by Carlos le Sage, Ph.D., Steffen Lawo, Ph.D., and Benedict C.S. Cross, Ph.D., (Horizon Discovery, United Kingdom). In their review, the authors discuss how CRISPR-Cas9 systems are being used widely throughout the drug discovery process and the…

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Coronavirus Live Updates: South Korea Raises Threat Alert Level

Here’s what you need to know: ImageSpraying disinfectant on Sunday at a market in Daegu, the southeastern city where many of South Korea’s coronavirus infections have been confirmed.Credit…Yonhap, via Agence France-Presse — Getty Images South Korea’s leader urges an ‘all-out, concerted response.’ President Moon Jae-in on Sunday put South Korea on the highest possible alert…

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