In the Global South less than one-third of high blood pressure patients treated

IMAGE: Professor Till Bärnighausen Alexander von Humboldt University Professor Director, Heidelberg Institute of Global Health Heidelberg University Hospital and the Medical Faculty of Heidelberg view more  Credit: Heidelberg University Healthcare in low- and middle-income countries is poorly prepared for the increasing number of high blood pressure (ie hypertension) disorders. More than two-thirds of all people affected…

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X-ray laser sight reveals drug targets

Researchers from the Moscow Institute of Physics and Technology have published a review on serial femtosecond crystallography, one of the most promising methods for analyzing the tertiary structure of proteins. This technique has rapidly evolved over the past decade, opening new prospects for the rational design of drugs targeting proteins previously inaccessible to structural analysis.…

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Taking out the protein garbage becomes more difficult as neurons age

IMAGE: Aberrantly formed autophagosomes accumulate in neuron of an aged mouse. view more  Credit: Andrea Stavoe, Penn Medicine; eLife PHILADELPHIA – Cells dispose of harmful “trash” through autophagy, a normal and necessary process in which aggregated proteins and dysfunctional structures are handled. If any part of this fails, waste builds up inside cells, eventually killing them.…

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