Research shows cytonemes distribute Wnt proteins in vertebrate tissue

Scientists have made a pivotal breakthrough in understanding the way in which cells communicate with each other. A team of international researchers, including experts from the University of Exeter’s Living Systems Institute, has identified how signalling pathways of Wnt proteins – which orchestrate and control many cell developmental processes – operate on both molecular and…

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Autism gene study finds widespread impact to brain’s growth signaling network

JUPITER, FL — Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds. The study from neuroscientist Damon Page, PhD, describes a new mechanism underlying…

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Nemours secures grant to study behavioral health interventions for teens with T1D

Jacksonville, FL (April 8, 2021) – Susana R. Patton, Ph.D., ABPP, CDCES Center Director of the Nemours Center for Healthcare Delivery Science in Florida, has secured a three-year, $900,000 NIH R01 grant entitled, “Coin2Dose: Behavioral economics to promote insulin bolus activity and improve HbA1c in teens.” Dr. Patton is the recipient of three concurrent R01…

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MHRP launches trial to evaluate IL-15 Agonist as therapy to reduce HIV reservoir

SILVER SPRING, Md. – The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research last week launched a Phase 2 clinical trial in Thailand to evaluate an interleukin-15 (IL-15) superagonist, ImmunityBio’s Anktiva® (also called N-803), administered during acute HIV infection as an experimental therapy to target establishment of the HIV…

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