Quenching an Ache to Celebrate

Morgan Clark walked into the bedroom of his fiancé, Elizabeth Reilly, on March 18 and found her sobbing. The devastating effects of the coronavirus forced the couple to move their originally scheduled wedding date up to March 22, from May 8. And they had to change the location of the church, from the Incarnation Anglican…

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Trastuzumab achieves slight reduction in recurrence for women with HER2-positive DCIS

The addition of the monoclonal antibody therapy Trastuzumab to radiotherapy did not reach the protocol objective of a 36% reduction in the ipsilateral breast tumor recurrence rate for women with HER2-positive ductal carcinoma in situ (DCIS) on the NRG Oncology clinical trial NSABP B-43. The trial did find a statistically non-significant, modest (19%) reduction in…

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Trastuzumab combined with trimodality treatment does not improve outcomes for patients

Results of the NRG Oncology clinical trial RTOG 1010 indicated that the addition of the monoclonal antibody trastuzumab to neoadjuvant trimodality treatment did not improve disease-free survival (DFS) outcomes for patient with HER2 overexpressing local and locally advanced esophageal adenocarcinoma. These results were recently, orally presented during the virtual Annual Meeting of the American Society…

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