UC consortium launches first clinical trial using CRISPR to correct sickle cell gene

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient’s own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics…

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Kids’ metabolic health can be improved with exercise during pregnancy: here’s why

BOSTON – (March 25, 2021) – A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring. According to researchers, the key lies with a protein called SOD3, vitamin D and adequate exercise, with the outcomes possibly forming the first steps to designing rational diet and exercise programs…

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Researchers develop tool to simplify diagnoses for children facing medical complexities

LOWELL, Mass. – Too often, contends UMass Lowell faculty researcher Brenna Morse, children with complex chronic medical conditions spend days in the hospital undergoing tests for what could be a simple diagnosis. The challenges include, she says, some children with medical complexities, such as severe neurological conditions and functional impairments, cannot easily signal that they…

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SwRI to develop AI for integrated corridor management traffic solutions for Tennessee DOT

SAN ANTONIO – March 30, 2021 – Southwest Research Institute, in collaboration with Vanderbilt University, is developing machine learning algorithms to help the Tennessee Department of Transportation (TDOT) coordinate traffic management and incident response along portions of Interstate 24 in the rapidly growing Nashville region. The project will use artificial intelligence to enhance an integrated…

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M. Wells Offers Its Cassoulet Bowls

Cassoulet season has ended, but the handmade bowls that M. Wells in Long Island City, Queens, commissioned to bake and serve theirs this year are timeless. The blue-and-white pottery pieces, in slightly varied designs and tones, can just as easily hold servings of bouillabaisse or be used for summer berries, cherries, a thatch of coleslaw…

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