Hyperactive FOXA1 reprograms endocrine-resistant breast cancer to become metastatic

A team led by researchers at Baylor College of Medicine and Harvard Medical School has unveiled a novel mechanism that helps explain how endocrine-resistant breast cancer acquires metastatic behavior, opening the possibility of new therapeutic strategies. Published in the Proceedings of the National Academy of Sciences, the study shows that hyperactive FOXA1 signaling, which previously…

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Training the brain: resilience program helps student-athletes adjust to college life

Imagine the impact on first-year college student-athletes in highly competitive programs if you could teach them resilience – if they learned skills to cope with high expectations, challenging academic courses, rigorous training and physical injuries, homesickness and even the stressors of life beyond college. In newly published research, a unique and expanding program at the…

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Black Women Reign at Beauty Pageants

When Zozibini Tunzi of South Africa was named Miss Universe on Sunday, her crowning signified a milestone: the first year that four of the major beauty pageants had simultaneously awarded the top prize to a black woman. Pageants have long been criticized for their antiquated beauty standards and, in many cases, outright racism or gender…

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The Most-Read Food Stories of 2019

Julia Moskin, Melissa Clark and Pete Wells try the new fake meats. The Impossible Burger bested the competition in a blind tasting of six national brands. The taste test replicated the experience of a home cook: Each burger was seared in canola oil and served in a potato bun. People complaining about the health implications…

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The I.R.S. Sent a Letter to 3.9 Million People. It Saved Some of Their Lives.

Three years ago, 3.9 million Americans received a plain-looking envelope from the Internal Revenue Service. Inside was a letter stating that they had recently paid a fine for not carrying health insurance and suggesting possible ways to enroll in coverage. New research concludes that the bureaucratic mailing saved lives. Three Treasury Department economists have published…

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