Still not enough women and older adults in cholesterol drug trials, study finds

Although heart disease is the leading cause of death in women, and older adults are more likely to have heart and vascular disease than young people, randomized clinical trials testing medications to lower cholesterol have historically underenrolled both groups. Randomized clinical trials generate the best evidence regarding the benefits or harms of given drug, and…

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RIHN taking initiative on discussion toward ‘new life’ after COVID-19 pandemic

The initiative of Covid-19 and Sustainable Transitions was inspired by a blog by the leadership of the Systems of Sustainable Consumption and Production Knowledge-Action Network and began in late-March in the form of an interactive online Open Forum, which has now developed into a diverse community of over 100 people including scientists, economists, and educators.…

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No evidence blanket ‘do-not-resuscitate’ orders for COVID-19 patients are necessary

DALLAS, May 22, 2020 — It’s inappropriate to consider blanket do-not-resuscitate orders for COVID-19 patients because adequate data is not yet available on U.S. survival rates for in-hospital resuscitation of COVID-19 patients and data from China may not relate to U.S. patients, according to a new article published today in Circulation: Cardiovascular Quality and Outcomes,…

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Glucose levels linked to maternal mortality even in non-diabetic women

An elevated pre-pregnancy hemoglobin A1c–which measures average blood glucose concentration–is associated with a higher risk of adverse pregnancy outcomes even in women without known diabetes, according to a new study published this week in PLOS Medicine by Joel Ray of ICES and the University of Toronto, Canada, and colleagues. Diabetes mellitus and obesity are both…

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The Lancet: First human trial of COVID-19 vaccine finds it is safe and induces rapid immune response

The first COVID-19 vaccine to reach phase 1 clinical trial has been found to be safe, well-tolerated, and able to generate an immune response against SARS-CoV-2 in humans, according to new research published in The Lancet. The open-label trial in 108 healthy adults demonstrates promising results after 28 days–the final results will be evaluated in…

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