Bone marrow-on-a chip provides new research directions for Shwachman-Diamond Syndrome

A new research tool that mimics the behavior of diseased bone marrow provides a new strategy for understanding the bone marrow disease, Shwachman-Diamond syndrome (SDS), and hopefully, developing new treatments. With SDS, bone marrow fails to produce blood cells normally, leading to bone marrow failure and an increased risk of leukemia. In a research paper…

Details

100 years after development, TB vaccines vary in ability to stimulate immune components

Each year, more than 100 million newborns around the world receive vaccinations against Mycobacterium tuberculosis, or TB, which infects about one-quarter of the world’s population. Facilities across the world produce several different formulations of these vaccines, known as Bacille Calmette GuĂ©rin (BCG) vaccines. These are given interchangeably, yet new research from the Precision Vaccines Program…

Details

Ethics and Human Research, January-February 2020

Crowdsourced Research: Vulnerability, Autonomy, and Exploitation Adrian Kwek The use of online crowdsourcing platforms to recruit research participants has become ubiquitous in social, behavioral, and educational research. In what sense are crowd workers vulnerable as research participants, and what should ethics reviewers look out for in evaluating a crowdsourced research protocol? The article examines these…

Details

Protein levels in urine after acute kidney injury predict future loss of kidney function

High levels of protein in a patient’s urine shortly after an episode of acute kidney injury is associated with increased risk of kidney disease progression, providing a valuable tool in predicting those at highest risk for future loss of kidney function. This finding, published Jan. 27 in JAMA Internal Medicine by Vanderbilt University Medical Center…

Details

General population screening reduces life-threatening diabetic ketoacidosis, new research shows

NEW YORK- January 28, 2020 –JDRF, the leading global organization funding type 1 diabetes (T1D) research, today announced new research that found widespread screening for islet autoantibodies reduced the occurrence of life-threatening diabetic ketoacidosis (DKA) among children with pre-symptomatic T1D. The JDRF-funded research study known as Fr1da was published in the Journal of the…

Details

Does news coverage of crashes affect perceived blame?

Despite an ever-rising number of pedestrian and bicyclist deaths on U.S. roads each year, there’s no widespread public pressure to improve road safety — a situation influenced by how news articles about auto-pedestrian/bicyclist crashes are written, said Tara Goddard, Texas A&M assistant professor of urban planning. “Adopting simple improvements in crash reporting offers a potentially…

Details