A mechanism that makes infants more likely than adults to die from sepsis is discovered

IMAGE: Scientists at the Center for Research on Inflammatory Diseases (CRID) show why pediatric patients with sepsis suffer from more inflammation and organ injury than adults. New treatment strategies may be… view more  Credit: image: Mariana J. Kaplan / NIAMS Systemic Autoimmunity Branch An immune mechanism that makes babies more likely than adults to die from…

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Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

IMAGE: Ramesh Shivdasani, MD, PhD view more  Credit: Dana-Farber Cancer Institute Two distinct subtypes discovered, each with dramatically different risks of recurrence Patients with more aggressive subtype can be monitored vigilantly for recurrence and possible treatment, while patients with the less aggressive subtype can be advised their prognosis is excellent BOSTON – Researchers have discovered two…

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Researchers reveal how protein mutation is involved in rare brain development disorder

Rearing its head in infancy, Christianson Syndrome is a rare disorder whose symptoms include intellectual disability, seizures and difficulty standing or walking. Although it is becoming increasingly diagnosed, with little being known about the neural mechanism behind the disease, therapeutic options for patients remain limited. Now, researchers at McGill University focusing on the intellectual disability…

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PathMaker Neurosystems is named as recipient of France’s top prize for innovation

BOSTON, MASSACHUSETTS, & PARIS, FRANCE, June 26, 2019 – PathMaker Neurosystems Inc. (“PathMaker”) is very pleased to announce that it has been named as the 2019 recipient of the CCI France International Trophy for Innovation at this year’s Trophées CCI France International. PathMaker Neurosystems, a clinical-stage bioelectronic medicine company developing breakthrough non- invasive systems for…

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Scientists discover autoimmune disease associated with testicular cancer

Using advanced technology, scientists at Chan Zuckerberg (CZ) Biohub, Mayo Clinic and University of California, San Francisco (UCSF), have discovered an autoimmune disease that appears to affect men with testicular cancer. Called “testicular cancer-associated paraneoplastic encephalitis,” the disease causes severe neurological symptoms in men. They progressively lose control of their limbs, eye movements, and, in…

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WVU researchers map crystals to advance treatments for stroke, diabetes, dementia

MORGANTOWN, W.Va.–Medications attach to the proteins in our bodies the way spacecrafts dock into the International Space Station. Describing that process in detail can reveal a lot about how the medications work–and what form new medications should take. Researchers at West Virginia University have mapped the crystal structure of a protein that resides in our…

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