Hitting the nail on the head: overcoming therapeutic resistance in lung cancer

A protein highly expressed in lung cancer cells drives resistance to targeted therapies, report researchers at the Medical University of South Carolina in the Journal of Thoracic and Cardiovascular Surgery. In preclinical experiments, the researchers showed that inhibiting the protein caused the death of non-small cell lung cancer cells that had become resistant to therapy.…

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Ludwig Chicago study identifies a novel drug target for the control of cancer metastasis

AUGUST 24, 2020, NEW YORK – Researchers led by Ludwig Chicago Co-director Ralph Weichselbaum and Ronald Rock of the University of Chicago have identified in preclinical studies a potential drug target for curtailing cancer metastasis. Their study, published in the Proceedings of the National Academy of Sciences, describes how a compound named 4-hydroxyacetophenone (4-HAP) activates…

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Citizens’ adherence to COVID-19 social distancing measures depends on government response

A new study conducted by a team of researchers, including University of Colorado Denver Business School associate professor Jiban Khuntia, PhD, found while social distancing is an effective preventative measure in the fight against COVID-19, there are significant variations being observed in how and why individuals follow the restrictions. The reasons ascribed in the study…

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