PEPTIC trial comparing strategies to prevent stress ulcers in ICU patients needing mechanical ventilation

What The Study Did: Researchers report on a randomized clinical trial that compared two strategies (proton pump inhibitors vs. histamine-2 receptor blockers) to prevent stress ulcers among adult patients in intensive care units who needed mechanical ventilation. The trial was conducted at 50 ICUs in five countries to compare in-hospital death rates using the two strategies. The…

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Green in tooth and claw

Go ahead, take a big bite. Hard plant foods may have made up a larger part of early human ancestors’ diet than currently presumed, according to a new experimental study of modern tooth enamel from Washington University in St. Louis. Scientists often look at microscopic damage to teeth to infer what an animal was eating.…

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Rich rewards: Scientists reveal ADHD medication’s effect on the brain

Attention-deficit hyperactivity disorder (ADHD) is a neurobiological disorder characterized by symptoms of hyperactivity, inattention and impulsivity. People with the condition are often prescribed a stimulant drug called methylphenidate, which treats these symptoms. However, scientists do not fully understand how the drug works. Now, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST)…

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Psychedelic drugs could help treat PTSD

Clinical trials suggest treatment that involves psychedelics can be more effective than psychotherapy alone. More than three million people in the United States are diagnosed each year with post-traumatic stress disorder, whose symptoms include nightmares or unwanted memories of trauma, heightened reactions, anxieties, and depression–and can last months, or even years. People with PTSD–difficulty recovering…

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