Taco Pizza and Other Stories

Good morning. It’s Caucus Day in Iowa, and a chunk of our newsroom is hunkered down in Des Moines, getting ready to report what’s happening into the night and early-morning hours of Tuesday. I hope you’ll follow along on our home page, and participate in our efforts to understand the news of the day and…

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J. Lo and the Power of 50

Fifty won the Super Bowl. Fifty years between wins for the Kansas City Chiefs, and 50-year-old Jennifer Lopez, whose halftime performance in a series of barely-there Versace bodysuits sent social media into something of a meltdown. More than four decades ago, Gloria Steinem crafted an aphorism that went down in history when, on her 40th…

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Helping Teenagers With Menstrual Pain

Period-related pain, medically known as dysmenorrhea, colloquially often called “cramps,” should not prevent an adolescent from participating fully in school, in sports, in social life. If that’s happening on a regular basis, she needs evaluation and help and support — from her family, and from the medical profession. “Painful periods can be very debilitating; I’ve…

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Building a safer CAR-T therapy

FEBRUARY 3, 2020, NEW YORK — A Ludwig Cancer Research study has devised a new type of chimeric antigen-receptor (CAR) T cell–a family of promising immunotherapies for cancer–that can be switched on and off on demand. The study, led by Melita Irving of the Lausanne Branch of the Ludwig Institute for Cancer Research, George Coukos,…

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FDA clears investigational new drug application for Calibr’s ‘switchable’ CAR-T therapy

LA JOLLA, CA — Calibr, the drug discovery and development division of Scripps Research, today announced that the U.S. Food and Drug Administration has given clearance to the Investigational New Drug (IND) application for Calibr’s “switchable” CAR-T cell therapy, which is being evaluated for the treatment of certain cancers, including relapsed/refractory B-cell malignancies such as…

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