Clinical trial at IU School of Medicine improves treatment of genetic rickets

IMAGE: Erik Imel, MD view more  Credit: Indiana University School of Medicine A new study shows a drug developed in conjunction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies. The findings are published in Lancet. X-linked hypophosphatemia, or XLH, is a…

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A PCR statement on behalf of PCR and the EAPCI

Paris, France, 21 May 2019. Heart failure is a common cardiovascular disorder with ominous prognosis despite significant therapeutic advances. Mitral regurgitation (MR, leaking of the mitral valve within the heart) affects at least 50% of patients with heart failure and is independently associated with worse prognosis. Timely diagnosis is essential, and management is complex, requiring…

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PCR statement on evolving indications for transcatheter aortic valve implantation

Paris, France, 21 May 2019. Severe symptomatic aortic stenosis, a degenerative disease-causing calcification and immobility of the aortic valve leaflets leading to left ventricular outflow obstruction, is the most common valve lesion leading to intervention in Europe and the USA. Symptoms include heart failure, syncope and angina, and have a dismal prognosis if left untreated.…

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A new approach to targeting cancer cells

IMAGE: The Pellecchia lab at UC Riverside is working on an approach in which effective drugs can be obtained by appropriately designing molecules to contain an aryl-fluoro sulfate (the chemical group… view more  Credit: Pellecchia lab, UC Riverside. RIVERSIDE, Calif. — A University of California, Riverside, research team has come up with a new approach to…

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