Combination drug therapy for childhood brain tumors shows promise in laboratory models

In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either drug alone in decreasing the growth of pediatric low-grade gliomas. These cancers are the most…

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Coronavirus Live Updates: U.S. Cruise Ship Passengers Evacuated From Japan; Taiwan Reports First Death

Here’s what you need to know: Flights carrying American passengers from a cruise ship took off from Japan. ImageThe Daikoku Pier Cruise Terminal, where the Diamond Princess is docked in Yokohama, Japan, south of Tokyo.Credit…Franck Robichon/EPA, via Shutterstock American passengers evacuated a cruise ship that has been quarantined for more than a week in the…

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Brian Noviski, Paul Harris

Brian Neil Noviski and Paul Elliott Harris are to be married Feb. 16 at Alo, a restaurant in Toronto. Sandra L. Ruch, a registered officiant with the province of Ontario, is to officiate. Mr. Noviski (left), 48, is the head of global architecture and design for Restaurant Brands International, which owns multiple fast-food brands in…

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Noah Mamis, Jason Ziplow

Noah Alexander Mamis and Dr. Jason Lee Ziplow are to be married Feb. 16 at the Angel Orensanz Foundation in Manhattan. Rabbi Stuart W. Gershon is to officiate. Mr. Mamis (left), 33, is the director of policy and research for the Democratic Majority Conference in the New York State Senate in Manhattan. He graduated from…

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