The Never-Ending Date

Daniel Paul Shear stopped at a red light in North Hollywood, Calif., in 2017 long enough to snap a photo of the Idle Hour bar, a building in the shape of a whiskey barrel, to send to Nora Charlotte Tillmanns. “I’m a native Angelino and I love fun design,” said Ms. Tillmanns, 32, who got…

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COVID-19 morbidity and mortality in people with rheumatic diseases

Arani Vivekanantham and colleagues investigated the association between RA and the risk of COVID-19 diagnosis, hospitalization with COVID-19,and COVID-19-related death. This population-based cohort study including all individuals registered in the Information System for Research in Primary Care (SIDIAP)- which covers over80% of the population of Catalonia, Spain. This information was linked to region-wide SARS-CoV-2 testing,…

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The true spread of SARS-CoV-2 infection is much greater than that observed by capturing only swab-diagnosed COVID-19 cases

As part of the MAINSTREAM project, Favalli and colleagues conducted a seroprevalence cross-sectional study between 4th May and 16th June 2020toestimate the prevalence of anti-SARS-CoV-2 antibodies in a large cohort of people with rheumatoid arthritis (RA) or spondyloarthritis (SpA) treated with biologic or targeted synthetic disease modifying anti rheumatic drugs (b/tsDMARDs) in a COVID-19 high-endemic…

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Researchers find losartan is not effective in reducing hospitalization from mild COVID-19

MINNEAPOLIS/ST. PAUL (06/18/2021) — University of Minnesota Medical School researchers determined that the common blood pressure medication, losartan, is not effective in reducing hospitalization for mildly-ill COVID-19 outpatients. In the multicenter, randomized, double-blinded clinical trial, non-hospitalized patients recently diagnosed with COVID-19 were given either losartan or a placebo and monitored for 15 days. The study’s…

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Overcoming a newly recognized form of resistance to modern prostate cancer drugs

IMAGE: Neuroendocrine prostate cancer cells. view more  Credit: Dr. Aaron Udager, Michigan Medicine Cancer cells have an uncanny ability to evolve and adapt to overcome the treatments used against them. While patient survival has been extended by modern drugs that block the production or action of male hormones that fuel prostate cancer — androgen receptor inhibitors…

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Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?

IMAGE: Laura Volpicelli-Daley view more  Credit: UAB BIRMINGHAM, Ala. – Will a reduction in tau protein in brain neurons protect against Parkinson’s disease and Lewy body dementias? A new study, published in the journal eNeuro, suggests the answer is no. If this is borne out, that result differs from Alzheimer’s disease, where reducing endogenous tau levels…

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