COMBAT study preliminary results show response of 32% in treatment of pancreatic tumors

SCOTTSDALE, Ariz. — Aug 11, 2020 — Working with an international team of researchers, HonorHealth Research Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, were instrumental in one of the first clinical trials showing how pancreatic cancer patients can benefit from immunotherapy, according to a four-year study published in…

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COVID-19 clinical trials lack diversity

Despite disproportionately higher rates of COVID-19 infection, hospitalization and death among people of color, minority groups are significantly underrepresented in COVID-19 clinical trials, according to a new perspective authored by faculty from the University of Georgia and University of Colorado and pharmacists from Phoebe Putney Memorial Hospital in Albany. Published by the New England Journal…

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New prediction model can forecast personalized risk for COVID-19-related hospitalization

CLEVELAND – Cleveland Clinic researchers have developed and validated a risk prediction model (called a nomogram) that can help physicians predict which patients who have recently tested positive for SARS-CoV-2, the virus that causes COVID-19, are at greatest risk for hospitalization. This new model, published in PLOS One, is the second COVID-19-related nomogram that the…

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Building the batteries of cells

Mitochondria are the powerhouse of cells which continuously convert energy from food into the chemical energy currency called ATP. This essential process depends on large protein complexes within the inner membrane of mitochondria acting similar to batteries. A new study, led by Dr. Ruchika Anand and Prof. Andreas Reichert, Heinrich-Heine-University Duesseldorf, Institute of Biochemistry and…

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Scientists found genes that help cancer cells to penetrate the brain

An international team of scientists, including a researcher from Sechenov University, reviewed scientific articles on proteins (and genes encoding them) that help cancer cells enter the brain. An understanding of the processes that facilitate the formation of metastases in the brain will allow scientists to create new methods for cancer diagnosis and treatment. Details of…

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Bouncing, sticking, exploding viruses: Understanding the surface chemistry of SARS-CoV-2

Researchers at Michigan Tech, TÜV SÜD UK National Engineering Laboratory and University of Edinburgh call for increased research on virus surface stability and interaction in “Surface Chemistry Can Unlock Drivers of Surface Stability of SARS-CoV-2 in Variety of Environmental Conditions” in the Cell Press journal Chem. They highlight the need to understand the different environmental…

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Spirits Distilled on the Farm

Here’s farm to glass. Potatoes, cucumbers, wheat, rye and herbs harvested from the fields of Foster Farm in Sagaponack, N.Y., go into the spirits that brother and sister, Dean and Marilee Foster, have been making for the past three years. “We knew the farm couldn’t survive on just potatoes,” said Mr. Foster, a sixth-generation farmer.…

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