Study identifies potential drug treatments for telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely. Using cells donated by patients with the disease, researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center identified several small molecules that appear to reverse this cellular aging process.…

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TGF-β-driven reduction of CYGB is associated with oxidative DNA damage of HSCs in NASH

In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for…

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When E.V.O.O. Met Chocolate

Kosterina, an olive oil company in the Peloponnese region of Greece that uses native koroneiki olives, has introduced chocolate bars, the dark chocolate blended with the extra-virgin olive oil. The result is rich, silky chocolate in some uncommon Mediterranean flavors like fig and balsamic vinegar; almond butter with vanilla; and nuts, including walnuts and pistachios,…

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A Glass to Keep Half Full

Even that pour of club soda will take on a springtime rosé hue in this new glass. It comes in a stemless shape, now something of a classic, and has a bubbly pattern in pale salmon pink that deepens from top to bottom. It’s a fairly substantial glass, holding 16 ounces, and could even be…

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Rezdôra Sells Its Pastas to Go

Before the pandemic, a reservation at Rezdôra was a challenge, and now it’s not possible to dine at Stefano Secchi and David Switzer’s year-old restaurant, featuring the food of Emilia-Romagna. But you can try a plate of the highly regarded homemade pasta, which impressed Pete Wells to the tune of three stars. Mr. Secchi is…

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