Cancer immunotherapy drugs, which spur the body’s own immune system to attack tumors, hold great promise but still fail many patients. New research may help explain why some cancers elude the new class of therapies, and offer some clues to a solution. The study, published on Thursday in the journal Cell, focuses on colorectal and…
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Ralph Metzner, a psychotherapist who began his career working with Timothy Leary on controversial studies at Harvard involving LSD and other drugs, then spent a lifetime exploring and writing about expanded consciousness in all sorts of cultures and settings, died on March 14 at his home in Sonoma, Calif. He was 82. His wife, Cathy…
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Though “The Devil Wears Prada” may have been unintentionally documentary, not every viper pit cliché about fashion and its affiliates holds true. The loopy, fragile and gifted individuals who populate that world also often operate as an extended family, albeit a loose-knit and occasionally dysfunctional one. Seldom is this more evident than when trouble befalls…
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Attorney General Letitia James of New York said on Thursday that she had filed a lawsuit against a for-profit stem cell clinic, Park Avenue Stem Cell, claiming it performed unproven, rogue procedures on patients with a wide range of medical conditions, from erectile dysfunction to heart disease. “Misleading vulnerable consumers who are desperate to find…
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Laure Heriard Dubreuil says she’s been barefoot for the past two weeks. She was on vacation in Mustique; now she’s back in New York, at the Soho outpost of the Webster, the luxury boutique she cofounded in Miami in 2009 (other branches are in Houston; Costa Mesa, California; and Bal Harbour, Florida). We’re on the…
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Before travelers could fly there, St. Louis, on the Mississippi River, was a natural point of continental convergence for rails, trails and sails, the gateway to the West in the 19th century. That traffic, and the industry that grew up around it, created a legacy of wealth and power that is reflected in the city’s…
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On Thursday afternoon, former vice president and potential presidential candidate Joe Biden released a video in which he discussed the importance of personal space. “Social norms have begun to change,” he said. “They’ve shifted, and boundaries of protecting personal space have been reset — and I get it.” Mr. Biden was responding to allegations by…
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The martini is a simple cocktail achieved by complex means. Choices along the way include gin or vodka, shaken or stirred, olive or twist, bitters or no, wet or dry. At Abigail Hall, a new restaurant in Portland, Ore., the order is accomplished in only two steps: Grab bottle of martinis from the freezer. Pour…
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An important omission on the menu at Taverna Kos in Astoria, Queens, is the enormous plate of feta you may see passing your table en route to a smarter party of people. Heaps of the imported cheese, which the restaurant buys in 28-pound containers, come flecked with dried oregano and slicked with olive oil, and…
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Wyatt Cenac was lapping the competition. He was speaking softly in paragraph-long thoughts about his HBO show, “Wyatt Cenac’s Problem Areas,” his love for animation and his relationship with his modest fame. Simultaneously, he was winning an unspoken competition at Buzz-a-Rama, the only place in New York City where a comedian can destroy all takers…
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