Missing link in coronavirus jump from bats to humans could be pangolins, not snakes

As scientists scramble to learn more about the SARS-CoV-2 coronavirus, two recent studies of the virus’ genome reached controversial conclusions: namely, that snakes are intermediate hosts of the new virus, and that a key coronavirus protein shares “uncanny similarities” with an HIV-1 protein. Now, a study in ACS’ Journal of Proteome Research refutes both ideas…

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FDA approves ozanimod, a drug invented at Scripps Research, for multiple sclerosis

LA JOLLA, CA — The U.S. Food and Drug Administration has approved ozanimod, an immune-modulating therapy invented at Scripps Research, for the treatment of adults with relapsing forms of multiple sclerosis. The drug is also in advanced clinical development for adults and children with moderate-to-severe ulcerative colitis and Crohn’s disease. In patient studies supporting ozanimod’s…

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Mount Sinai researchers unveil mechanisms to prevent Crohn’s disease

(New York, NY – March 26, 2020) – In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD. “Early identification of individuals at high…

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Moffitt researchers discover novel role of specific histone deacetylase in lung cancer

TAMPA, Fla. – The survival rates for patients with non-small cell lung cancer (NSCLC) have improved greatly over the past decade thanks to several new targeted treatment options for patients. However, lung cancer still remains the number one cause of cancer-related morality, leading to approximately 154,000 deaths each year in the United States. Many patients…

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Texas Biomed accelerates multi-species study to identify COVID-19 animal model

San Antonio, Texas (March 26, 2020) – Scientists at Texas Biomedical Research Institute (Texas Biomed) today announced the launch of a comprehensive research initiative to investigate multiple animal species and their response to the novel coronavirus disease (COVID-19). This study expands on a previously launched study to validate a baboon animal model for SARS-CoV-2, the…

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Worldwide scientific collaboration unveils genetic architecture of gray matter

The cerebral cortex is the relatively thin, folded, outer “gray matter” layer of the brain crucial for thinking, information processing, memory, and attention. Not much has been revealed about the genetic underpinnings that influence the size of the cortex’s surface area and its thickness, both of which have previously been linked to various psychiatric traits,…

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Executive function in women post-menopause

AURORA, Colo. (March 26, 2020) – Assessing adverse childhood experiences and current anxiety and depression symptoms may help ease cognitive distress in women who have undergone a surgical menopause for cancer risk-reduction, or RRSO, according to a new study published in Menopause. Researchers, including Dr. Neill Epperson of the University of Colorado Anschutz Medical Campus,…

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