Hinge-like protein may open new doors in cystic fibrosis treatment

IMAGE: A potentiator (orange) binds to a protein ‘hotspot,’ altering the molecule’s conformation. view more  Credit: Laboratory of Membrane Biology and Biophysics at The Rockefeller University In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which is…

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UM researchers land NIH contract to develop opioid addiction vaccine

IMAGE: Montana Gov. Steve Bullock (right) meets with Dr. Jay Evans, director of UM’s Center for Translational Medicine. view more  Credit: University of Montana file photo MISSOULA – The University of Montana has received a $3.3 million contract from the National Institutes of Health to develop an innovative vaccine targeting opioid addiction. The principal investigator on…

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University of Pittsburgh group brings computation and experimentation closer together

IMAGE: Frames from a 10 hour long time-lapse sequence with model prediction (red line) and explant spreading (dotted line). ‘Good’ models predict not only the extent of the movement but also… view more  Credit: MechMorpho Lab/University of Pittsburgh PITTSBURGH (July 9, 2019) … A bioengineering group from the University of Pittsburgh Swanson School of Engineering is…

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