Autism gene study finds widespread impact to brain’s growth signaling network

JUPITER, FL — Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds. The study from neuroscientist Damon Page, PhD, describes a new mechanism underlying…

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Nemours secures grant to study behavioral health interventions for teens with T1D

Jacksonville, FL (April 8, 2021) – Susana R. Patton, Ph.D., ABPP, CDCES Center Director of the Nemours Center for Healthcare Delivery Science in Florida, has secured a three-year, $900,000 NIH R01 grant entitled, “Coin2Dose: Behavioral economics to promote insulin bolus activity and improve HbA1c in teens.” Dr. Patton is the recipient of three concurrent R01…

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MHRP launches trial to evaluate IL-15 Agonist as therapy to reduce HIV reservoir

SILVER SPRING, Md. – The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research last week launched a Phase 2 clinical trial in Thailand to evaluate an interleukin-15 (IL-15) superagonist, ImmunityBio’s Anktiva® (also called N-803), administered during acute HIV infection as an experimental therapy to target establishment of the HIV…

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What Is Normal Life?

Want to get the At Home newsletter in your inbox? Sign up here. Welcome. What constitutes a return to “normal” life? Is it when schools and offices are open consistently? When we’ve reached herd immunity? When we no longer wear masks in the supermarket? On planes? (Will we ever not wear masks in stores and…

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