Gene therapy towards a clinical trial for gamma-sarcoglycanopathy, limb-girdle muscular dystrophy

Gamma-sarcoglycanopathy (LGMD2C) is one of the most common limb-girdle myopathies. It affects less than 10 people per 1,000,000 and is characterized by progressive muscle weakness in the pelvis (pelvic girdle) and shoulders (scapular girdle), linked to mutations in the SGCG gene encoding gamma-sarcoglycan. There is currently no cure for this neuromuscular disease. In this study,…

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Insilico to present at the 2019 Innovative China Conference

IMAGE: Alex Zhavoronkov, Ph.D., Founder and CEO of Insilico Medicine, to present at the 2019 Innovative China Conference on May 27, 2019 in Shenzhen. view more  Credit: Insilico Medicine Friday, May 24, 2019 – Insilico Medicine, a biotech company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results…

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Cancer cells are quick-change artists adapting to their environment

IMAGE: Microscopy image of glioblastoma stem cells growing in different microenvironments. view more  Until now, researchers have assumed that the growth of solid tumors originates from cancer stem cells characterized by specific surface markers, which develop in a fixed, hierarchical order. Accordingly, such cancer stem cells are responsible for tumor progression and produce specific types of…

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New study reveals gut is organized by function, and opportunities for better drug design

VIDEO: Scientists found that part of the gut’s immune system functions differently in distinct parts of the intestine. view more  As food enters the intestine, it embarks on windy, lengthy journey. For most of the route, its surroundings don’t appear to change much. But new research from Rockefeller’s Daniel Mucida shows that the food-processing canal consists…

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Study analyzes mortality risks among pro athletes

Professional football players appear to have a somewhat elevated risk of death, including higher risk of succumbing to cardiac and neurodegenerative diseases, compared with professional baseball players of similar age, according to new research. The findings raise important questions about sport-specific differences in disease development and the mechanisms that drive the elevated risk. Such mechanisms…

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Different types of nipples

The appearance of nipples can vary significantly from one person to another. There is no normal nipple and no formal medical description of nipple types. Nipples may be protruding, puffy, hairy, inverted, flat, bumpy, or a combination. Usually, the appearance of nipples makes no difference in how they function, and it poses no risks. Some…

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