Hormone therapy may increase cardiovascular risk during gender transition

DALLAS, February 18, 2019 — Patients receiving hormone therapy as part of their gender-transition treatment had an elevated risk for cardiovascular events, including strokes, heart attacks and blood clots, according to a study published in the American Heart Association’s journal Circulation. The results are based on analysis of medical records of 3,875 Dutch individuals who…

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Physicists pinpoint a simple mechanism that makes bacteria resistant to antibiotics

IMAGE: These are researchers Maikel Rheinstädter and Adree Khondker of McMaster University. view more  Credit: JD Howell, McMaster University Physicists at McMaster University have for the first time identified a simple mechanism used by potentially deadly bacteria to fend off antibiotics, a discovery which is providing new insights into how germs adapt and behave at a…

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Small cell lung cancer may respond to combination of immunotherapy and DNA damage repair inhibitors

IMAGE: Lauren Averett Byers, M.D. view more  Credit: MD Anderson Cancer Center Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair (DDR) achieved significant tumor regression in mouse models of small cell lung cancer (SCLC), suggesting a…

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Depression reversed in male mice by activating gene that helps excite neurons

IMAGE: This is Dr. Xin-Yun Lu, molecular behavioral neuroscientist at the Medical College of Georgia at Augusta University. view more  Credit: Phil Jones, Augusta University Senior Photographer AUGUSTA, Ga. (Feb. 18, 2019) – Directly activating a gene important to exciting our excitatory neurons and associated with major depression may help turn around classic symptoms like social…

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