(Boston)–Researchers have determined that after lungs recover from infection, alveolar macrophages (immune cells that live in the lungs and help protect the lungs against infection) are different in multiple ways and those differences persist indefinitely. How the lungs protect themselves when they are at their healthiest, like in young adult humans, is complex and only…
Details
WASHINGTON (January 28, 2020) — The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved $12.2 million to fund four studies comparing the most effective ways to treat a range of health conditions that impose high burdens on patients, their families and the healthcare system. The Board approved $4.2 million in funding for…
Details
American and British teams led by Drs Kohn (University of California, Los Angeles), Malech (NIH), Williams (Boston Children’s) and Trasher (Great Ormond Street Institute of Child Health) published yesterday in Nature Medicine the conclusive results of a gene therapy trial conducted in the United States and Great Britain in 9 patients with X-linked Chronic Septic…
Details
A new research tool that mimics the behavior of diseased bone marrow provides a new strategy for understanding the bone marrow disease, Shwachman-Diamond syndrome (SDS), and hopefully, developing new treatments. With SDS, bone marrow fails to produce blood cells normally, leading to bone marrow failure and an increased risk of leukemia. In a research paper…
Details
Published in Psychological Medicine, the research used fMRI scans to examine the brain activity of 13 people with a diagnosis of psychosis under the influence of a single dose of CBD or placebo and 16 controls whilst they were undertaking a memory task. The researchers showed that, during the task, there was a different pattern…
Details
Each year, more than 100 million newborns around the world receive vaccinations against Mycobacterium tuberculosis, or TB, which infects about one-quarter of the world’s population. Facilities across the world produce several different formulations of these vaccines, known as Bacille Calmette Guérin (BCG) vaccines. These are given interchangeably, yet new research from the Precision Vaccines Program…
Details
Crowdsourced Research: Vulnerability, Autonomy, and Exploitation Adrian Kwek The use of online crowdsourcing platforms to recruit research participants has become ubiquitous in social, behavioral, and educational research. In what sense are crowd workers vulnerable as research participants, and what should ethics reviewers look out for in evaluating a crowdsourced research protocol? The article examines these…
Details
High levels of protein in a patient’s urine shortly after an episode of acute kidney injury is associated with increased risk of kidney disease progression, providing a valuable tool in predicting those at highest risk for future loss of kidney function. This finding, published Jan. 27 in JAMA Internal Medicine by Vanderbilt University Medical Center…
Details
NEW YORK- January 28, 2020 –JDRF, the leading global organization funding type 1 diabetes (T1D) research, today announced new research that found widespread screening for islet autoantibodies reduced the occurrence of life-threatening diabetic ketoacidosis (DKA) among children with pre-symptomatic T1D. The JDRF-funded research study known as Fr1da was published in the Journal of the…
Details
Despite an ever-rising number of pedestrian and bicyclist deaths on U.S. roads each year, there’s no widespread public pressure to improve road safety — a situation influenced by how news articles about auto-pedestrian/bicyclist crashes are written, said Tara Goddard, Texas A&M assistant professor of urban planning. “Adopting simple improvements in crash reporting offers a potentially…
Details