Study finds racial disparities in breast cancer prognosis testing

Black women have higher recurrence and mortality rates than non-Hispanic white women for certain types of breast cancer, according to a University of Illinois Chicago researcher’s study published recently in JAMA Oncology. Dr. Kent Hoskins, associate professor in the UIC College of Medicine’s division of hematology/oncology, and co-leader of the Breast Cancer Research group in…

Details

Counting patients social determinants of health may help doctors avert fatal heart attacks

Doctors may be able to predict their patients’ risks of fatal coronary heart disease more accurately by taking into account the number of adverse social factors affecting them, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The researchers, whose findings appear Dec. 3 in Circulation, analyzed data from the…

Details

New biochemical clues in cell receptors help explain how SARS-CoV-2 may hijack human cells

The SARS-CoV-2 virus may enter and replicate in human cells by exploiting newly-identified sequences within cell receptors, according to work from two teams of scientists. The findings from both groups paint a more complete portrait of the various cellular processes that SARS-CoV-2 targets to not only enter cells, but to then multiply and spread. The…

Details

Creating a safe CAR T-Cell therapy to fight solid tumors in children

Chimeric Antigen Receptor T-cell therapy–CAR T–has revolutionized leukemia treatment. Unfortunately, the therapy has not been effective for treating solid tumors including childhood cancers such as neuroblastoma. Preclinical studies using certain CAR T against neuroblastoma revealed toxic effects. Now, a group of scientists at Children’s Hospital Los Angeles have developed a modified version of CAR T…

Details

Sloan Kettering Institute scientists solve a 100-year-old mystery about cancer

The year 2021 marks the 100th anniversary of a fundamental discovery that’s taught in every biochemistry textbook. In 1921, German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely inefficient manner: rather than “burn” it using oxygen, cancer cells do what yeast do — they ferment it. This oxygen-independent…

Details

Study suggests coffee temporarily counteracts effect of sleep loss on cognitive function

A new study exploring the impact of repeated sleep loss during a simulated working week has found that consuming caffeinated coffee during the day helps to minimize reductions in attention and cognitive function, compared to decaffeinated coffee1. While this effect occurred in the first three-to-four days of restricted sleep, by the fifth and final day,…

Details

Patients in cancer remission at high risk for severe COVID-19 illness

PHILADELPHIA–Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in JNCI Cancer Spectrum shows. Past reports have established an increased risk of severe disease and death for sick or hospitalized cancer patients with COVID-19 compared…

Details