Metformin is often used during pregnancy where the mother is suffering from polycystic ovary syndrome (PCOS). A study from the Norwegian University of Science and Technology (NTNU) has recently shown that this results in fewer miscarriages and premature births. But a companion Norwegian study shows that children who are exposed to metformin in the womb…
Alpha-1-antitrypsin is a protein produced by the liver. The protein gets secreted to the blood stream, where it circulates the body to protect the lungs. However, some people are born with genetic disorders that hinders production of this protein. These patients can suffer from decreased lung function, liver diseases and shortness of breath. In the…
It is common knowledge that as people grow older they lose a large part of their muscle mass – and neither are their bones what they once were. Researchers from Aarhus University, Denmark, working together with researchers at Erasmus Medical Center in Rotterdam have now studied a new group of medication which could prove beneficial…
IMAGE: Dr. Verian Bader and Ana Sánchez Vicente are members of the research team headed by Professor Konstanze Winklhofer (in the background) which has revealed a new role of the protein… view more Credit: RUB, Marquard Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell…
IMAGE: The neurons of the enteric nervous system — what role do they play in the regulation of the body’s immune response? view more Credit: Photo: Klose/Charité How can we further improve deep brain stimulation and its use in the treatment of neurological disorders? How does the nervous system regulate both protective and chronic immune responses?…
IMAGE: Structures of the catalytic domains of USP28 and USP25: USP28 is a constitutively active dimer and can bind and process ubiquitin (orange) at any time. In contrast, USP25 is a… view more Credit: Picture: Rudolf Virchow Center of experimental biomedicine / University of Wuerzburg The permanent interplay of protein production and degradation is a major…
IMAGE: Radiolabeled protein lights up tumor implanted in the arm of a mouse under a PET scan. The researchers hope to use scans like this one to to calculate in real… view more Credit: Sridhar Nimmagadda Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography (PET) scans to calculate in real…
Mike Greco, who was known to connoisseurs of Italian cuisine as “the Salami King” and “the Mayor of Arthur Avenue,” and whose salumeria has catered to old neighbors, visiting politicians and insatiable Bronx expatriates for more than six decades, died on March 22 in White Plains. He was 89. His death was confirmed by his…
The announcement by Chicago prosecutors on Tuesday that they were dropping all charges against the “Empire” actor Jussie Smollett was the latest turn in a strange and twisting case. And it enraged the city’s own mayor and police superintendent. Joe Magats, the prosecutor, said the charges were dropped after Mr. Smollett, accused of staging a…
Purdue Pharma, the maker of OxyContin, and its owners, the Sackler family, agreed to pay $270 million to avoid going to a state court trial over the company’s role in the opioid addiction epidemic that has killed more than 200,000 Americans over the past two decades. The payment, negotiated to settle a case brought by…