Lack of diversity in genomic databases may affect therapy selection for minority groups

ROCHESTER, Minn. — Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology. The researchers investigated the use of genomic databases and found that tumor mutation burden was significantly inflated in Black patients compared to White…

For good health, trust your gut

If it seems like your stomach has a mind of its own, you’re not wrong. University of Cincinnati assistant professor Ashley Ross says your body is full of neurons that regulate digestion, inflammation and a host of other biological processes. In her chemistry lab in UC’s College of Arts and Sciences, she is studying the…

Gene therapy using ‘zinc fingers’ may help treat Alzheimer’s disease, animal study shows

BOSTON – Researchers have used a genetic engineering strategy to dramatically reduce levels of tau–a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer’s disease–in an animal model of the condition. The results, which come from investigators at Massachusetts General Hospital (MGH) and Sangamo Therapeutics Inc., could lead to…

Early benefit assessment – the whole range

“The AMNOG procedure has passed its first practical test. It is practicable and can also be implemented in detail”, emphasized IQWiG’s Director Jürgen Windeler in October 2011, when the Institute had published its first early benefit assessment within the framework of the AM-NOG procedure (AMNOG = Act on the Reform of the Market for Medicinal…

COVID-19 in pregnancy associated with adverse outcomes for mother and baby

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnancy is associated with preeclampsia, stillbirth, preterm birth and other adverse outcomes, found new research published in CMAJ (Canadian Medical Association Journal) . “Our findings suggest that pregnant people with COVID-19 have an increased risk of high blood pressure, stillbirth and preterm birth. Their newborns…

Large-scale study finds AI-powered COVID-19 solution by RADlogics reduces turnaround time

MOSCOW, RUSSIA – Moscow Center for Diagnostics & Telemedicine and RADLogics shared the results of a large-scale study (Moscow Experiment on the Computer Vision for the Analysis of Medical Images – mosmed.ai, NCT04489992) conducted by the Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department. The clinical…