PHILADELPHIA–A prospective “PARP inhibitor” drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science. The team also showed that PARP inhibitor compounds can be “tuned” in the opposite way so that…
Rochester Institute of Technology’s National Technical Institute for the Deaf is one of four international innovators selected to create cost-effective packages of high-quality accessible children’s books in languages children use and understand. The initiative, from All Children Reading: A Grand Challenge for Development and the Global Book Alliance’s Begin With Books, enables the prize winners…
Social distancing has Americans mostly out of the places they usually gather and in their homes as we try to reduce the spread of COVID-19. But some buildings, such as hospitals and grocery stores, have to remain open, and at some point, most of us will go back to the office or workplace. What is…
The Sleep Research Society (SRS) has selected three outstanding sleep and circadian scientists as recipients of the 2020 Sleep Research Society awards, which recognize excellence in sleep and circadian research. “The Sleep Research Society awards recognize individuals who have made significant contributions to sleep and circadian science,” said SRS President Andrew D. Krystal, MD. “I…
Action real-time strategy video games such as World of Warcraft, Age of Empires, and Total War are played by millions. These games, which can be won through strategic planning, selective attention, sensorimotor skills, and teamwork place considerable demands on the brain. Research has shown that experience of playing games can improve cognitive development such as…
Here’s what you need to know: ImageDeserted streets this week in Milan, Italy’s commercial capital. The European Union has agreed to an aid package for countries like Italy that have been hit hard by the coronavirus pandemic.Credit…Alessandro Grassani for The New York Times E.U. officials agreed to spend heavily to shore up economies, but only…
It was the fliers bearing his photo that made Adam Witt suspect something had gone deeply wrong. Last week, Jersey Shore University Medical Center, where he worked as a nurse, posted the fliers at two security stations, declaring that he was persona non grata. “Mr. Witt is not allowed on property at JSUMC,” the writing…
It all started because DeRay Mckesson was cold. In 2014, when the school administrator–turned–activist set out to drive from his home in Minneapolis to Ferguson, Missouri, to protest the police shooting of Michael Brown, he threw on a blue vest he’d bought five years earlier on a trip to New York City. Soon, images of…
Every night around 7 P.M. Nashville time, Karen Elson beams onto Instagram. “A song a day keeps the blues away,” types the redhead, before launching into acoustic covers of jazz, rock n’ roll, and folk. The 41-year-old leans against custom wallpaper by the artist Costanza Theodoli-Braschi and wears all kinds of things—a T-shirt from the…
Last week, Vanity Fair Italy’s cover star was not a supermodel lounging on a yacht in an Etro caftan, or a movie star in Gucci, but rather a lung specialist in a starched white lab coat. In Britain, front line workers from the National Health Service graced four special edition covers of Grazia magazine. The…