Research group identifies potential therapeutic target for lupus

News Release 26-Mar-2021 Inhibiting IRE1α, a molecule activated by the endoplasmic reticulum in neutrophils, counters disease progression in lupus mice. Michigan Medicine – University of Michigan Research News A recent study published in JCI found that a neutrophil’s endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus.…

The persistent danger after landscape fires

Reactive oxygen species (ROS) cause oxidative stress at the cellular level. Research shows that this way, amongst others, they inhibit the germination capacity of plants, produce cytotoxins or exert toxic effects on aquatic invertebrates. Environmentally persistent free radicals (EPFR) are potential precursors of ROS because they can react with water to form these radical species.…