Magnetic field from MRI affects focused-ultrasound-mediated blood-brain barrier

IMAGE: In a mouse model study of MRI-guided focused ultrasound-induced blood-brain barrier (BBB) opening at MRI field strengths ranging from ­approximately 0 T (outside the magnetic field) to 4.7 T, the… view more  Credit: Washington University in St. Louis MRI-guided focused ultrasound combined with microbubbles can open the blood-brain barrier (BBB) and allow therapeutic drugs to…

Gene therapy offers long-awaited hope for children with rare, incurable disorder

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children’s Hospitals. The trial includes seven children aged 4 to 9 born with deficiency of AADC, an enzyme involved in the synthesis of neurotransmitters, particularly dopamine, that…

BU researchers develop novel, woman controlled contraceptive product

(Boston)–Despite the availability of numerous effective birth control methods, more than 40 percent of pregnancies worldwide are unintended. In addition to contributing significantly to population growth, unintended pregnancies can have pronounced adverse effects on maternal physical, mental and economic wellbeing. Researchers from Boston University School of Medicine (BUSM) and ZabBio (San Diego, CA) have developed…

$1M NIGMS grant gives students at Lewis Katz School of Medicine chance at early success

(Philadelphia, PA) – Rapid evolution in the field of biomedical research demands well-trained scientists. Adapting biomedical research training programs to keep up with the increasingly complex and interdisciplinary nature of the field, however, presents complex challenges for higher-education institutions. The Lewis Katz School of Medicine at Temple University, home to highly skilled researchers and professors…