Researchers at the LSTM’s Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis. The research, led by Dr Joseph Turner at LSTM’s Department of Tropical Disease Biology, in collaboration with Professor Samuel Wanji’s team at…
IMAGE: Structures of GPCRs solved with stabilizing mutations predicted by CompoMug. (a) serotonin 5-HT2c receptor (PDB:), (b) frizzled FZD4 receptor, © prostaglandin EP3 receptor and (d) cannabinoid CB2 receptor. Stabilizing amino… view more Scientists from the Moscow Institute of Physics and Technology (MIPT), the Skolkovo Institute of Science and Technology (Skoltech), and the University of Southern…
A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients. The trial used a treatment combination of ADI-PEG20, pemetrexed and cisplatin, which showed encouraging efficacy in patients with recurrent high-grade gliomas…
IMAGE: Michigan State University has landed a $1.8 million National Institutes for Health R01 grant to improve brain implants – “electroceuticals ” used to treat Alzheimer’s, Parkinson’s, depression and traumatic injuries…. view more Credit: Courtesy of MSU EAST LANSING, Mich. – Michigan State University has landed a $1.8 million National Institutes for Health R01 grant to…
IMAGE: New variants in the ENAM gene that codes enamelin were discovered in Parson Russell Terriers. view more In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4,…
A new study from the University of Colorado Anschutz Health and Wellness Center (AHWC) at the CU Anschutz Medical Campus revealed physical activity does more to maintain substantial weight loss than diet. The study, published in the March issue of Obesity, was selected as the Editor’s Choice article. “This study addresses the difficult question of…
IMAGE: This is Kevin Pearson in his lab at the University of Kentucky. view more Credit: UK Photo | Mark Cornelison LEXINGTON, Ky. (Jan. 4, 2019) — Using foreskin tissue from newborn circumcisions, a group of researchers have identified a potential cellular mechanism that connects a mother’s smoking while pregnant with an increased risk of offspring…
IMAGE: This is a baby wearing two of the patches developed by the team. view more Credit: University of Illinois Coordinated Science Laboratory. The bond between a parent and their child is forged within the first few weeks of life. The nurse places the baby in their parents’ arms where it will be comforted and rocked…
IMAGE: The body motion is cancelled and basis of the cilium is fixed. The blue line corresponds to the mathematical description of the position of the cilium. The red circle corresponds… view more Credit: Philip Bayly Human bodies have some built-in systems to care for themselves. The cells that line our lungs, nose, brain and reproductive…
You can now perform supercomputer simulations of the heart’s electrophysiology in real time on desktop computers and even cellphones. A team of scientists from Rochester Institute of Technology and Georgia Tech developed a new approach that can not only help diagnose heart conditions and test new treatments, but pushes the boundaries of cardiac science by…