Building a safer CAR-T therapy

FEBRUARY 3, 2020, NEW YORK — A Ludwig Cancer Research study has devised a new type of chimeric antigen-receptor (CAR) T cell–a family of promising immunotherapies for cancer–that can be switched on and off on demand. The study, led by Melita Irving of the Lausanne Branch of the Ludwig Institute for Cancer Research, George Coukos,…

FDA clears investigational new drug application for Calibr’s ‘switchable’ CAR-T therapy

LA JOLLA, CA — Calibr, the drug discovery and development division of Scripps Research, today announced that the U.S. Food and Drug Administration has given clearance to the Investigational New Drug (IND) application for Calibr’s “switchable” CAR-T cell therapy, which is being evaluated for the treatment of certain cancers, including relapsed/refractory B-cell malignancies such as…

HIT modernization crucial to improve healthcare for Native Americans and Alaska Natives

INDIANAPOLIS — The Indian Health Service (IHS), a division within the U.S. Department of Health and Human Services, needs technology improvements to enhance healthcare for Native Americans and Alaska Natives, according to a Health Affairs blog post written by Regenstrief Institute and Indiana University School of Medicine researchers. The authors urge Congress to support the…

ESMO reaffirms commitment to education as key lever to make cancer prevention effective

International survey results on public’s behaviours around cancer released Alarming contrast in responses between socio-economic groups ESMO highlights improved prevention knowledge and wider accessibility to care as key priorities Lugano, Switzerland, 4 February – Today on World Cancer Day, ESMO, the leading organisation for medical oncology, joins the Union for International…

New research finds that ACOs are struggling to integrate social services with medical care

New findings from a Dartmouth-led study, published in the February issue of Health Affairs, show that despite effort and attention on the part of some healthcare providers to better address their patients’ social needs–such as transportation, housing, and food–little progress is being made to integrate social services with medical care. Given the substantial impact of…

Putting precision oncology into practice

Rush University Medical Center is the first health care organization to launch medical record company Epic’s module for genomic results, giving providers the tools they need to tailor patient care at the molecular level. Rush will use the module as part of its Precision Oncology Center to integrate the power of genomic sequencing data into…

First-ever experimental Sudan virus specific antibody treatment protects animals

Army scientists working with partners from industry and academia have developed an experimental treatment that protects animals from Sudan virus, which is closely related to Ebola. Their work is published online today in the journal Proceedings of the National Academy of Sciences. There are six distinct species of ebolaviruses, which collectively pose a significant threat…