Bypassing clinical trials for a potential SARS-CoV-2 vaccine would be “catastrophic,” says Science Advances deputy editor Douglas Green in this Editorial. Instead, it’s vital to take time to ensure any vaccine candidate’s safety and investigate potential adverse effects, he says. A vaccine able to trigger strong neutralizing antibody responses in clinical tests will still not…
Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs). PRMTs have been gaining increasing attention in the scientific landscape due their role in several essential physiological processes and implication in various diseases, including…
EVANSTON, Ill. — Winter may be behind us, but do you remember the challenge of waking up on those cold, dark days? Temperature affects the behavior of nearly all living creatures, but there is still much to learn about the link between sensory neurons and neurons controlling the sleep-wake cycle. Northwestern University neurobiologists have uncovered…
NEW YORK – May 22, 2020 – The Cardiovascular Research Foundation (CRF) has announced that TVT Connect, the Structural Heart Summit, will take place online June 18-28, 2020. TVT Connect features expertly developed series, late-breaking clinical science, challenging cases, industry-sponsored sessions, and connection to a community of thought leaders from across the globe. “We transformed…
SILVER SPRING, Md.–Researchers have discovered that anti-obesity medications such as phentermine and topiramate, used individually or in combination, can significantly reduce weight regain in patients after Roux-en-Y gastric bypass surgery, according to a retrospective study published online in Obesity, the flagship journal of The Obesity Society. “Our study provides evidence that medications can help, especially…
WASHINGTON – (May 21,2020) — Children’s National Hospital is establishing a regional pediatric telehealth consortium in response to coronavirus with $928,000 in funding awarded by the Federal Communications Commission’s Wireline Competition Bureau. The funding, which is part of the FCC’s COVID-19 Telehealth Program, enables the nationally-ranked pediatric hospital to expand its telehealth platform to support…
Bottom Line: Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research Authors: The senior author was…
The deal with AstraZeneca is the fourth and by far the largest vaccine research agreement that the department has disclosed. The money will pay for a Phase 3 clinical trial of a potential vaccine in the United States this summer with about 30,000 volunteers. The H.H.S. statement said the agency and AstraZeneca “are collaborating to…
A group of 77 Nobel laureates has asked for an investigation into the cancellation of a federal grant to EcoHealth Alliance, a group that researches bat coronaviruses in China. The pre-eminent scientists characterized the explanation for the decision by the National Institutes of Health as “preposterous.” The agency said the investigation into the sources of…
SAN FRANCISCO — On his walking tours of the Tenderloin, a historically seamy neighborhood named for a cut of beef, Del Seymour passes Boeddeker Park, now a verdant jewel of urbanity. Eleven years ago, it was a notorious hellhole where Mr. Seymour, then a crack addict, dealer and pimp, shooed away do-gooders from the local…