Exercise offers ‘profound’ benefits for Friedreich’s ataxia, research suggests

A top exercise researcher at the University of Virginia School of Medicine is urging clinical trials of exercise in patients with Friedreich’s ataxia after finding that physical activity has a “profound” protective effect in mouse models of the debilitating genetic disease. Friedreich’s ataxia typically limits patients’ ability to exercise. But the new findings from UVA’s…

New mechanism underlying colorectal cancer reveals a crucial role for intestinal microbes

A collaborative study by research groups from the VIB-UGent Center for Inflammation Research and Ghent University uncovered a new mechanism causing colorectal cancer. The researchers found that abnormal expression of the protein Zeb2 affects the integrity of the intestinal wall or ‘epithelium’. This epithelium normally functions as a barrier to prevent infiltration by intestinal microbes.…

Including patients in hospital discharge communication would improve outcomes of care

Study by University of Warwick researchers shows UK patients are keen to receive discharge letters when they leave hospital UK hospitals send discharge letters to GPs as part of care handover, but practice of copying in patients is inconsistent Better information for patients following discharge from hospital could improve the outcomes of care, including avoiding…

NCRI Virtual: In conversation with…Vinay Prasad

Join Dr Vinay Prasad, a Haematologist-Oncologist and Associate Professor of Medicine at University of California San Francisco. Vinay studies cancer drugs, health policy and evidence-based medicine and, in conversation with Dr Richard Simcock from Brighton and Sussex University Hospitals NHS Trust, will discuss ‘the good, the bad and the ugly’ in clinical research; what we can…

Own a Piece of the Ritz

Would you like to own a set of six crystal Bar Hemingway martini glasses from the Ritz in Paris? At an auction from Sunday through Tuesday of tableware and other artifacts from the hotel, there are four lots of these, estimated at 400 to 600 euros (around $450 to $680). Or if your dining area…

A Platform for Your Wine Bottle

An unusual brass wine coaster just landed in the gift shop at the Glass House, the Philip Johnson residence in New Canaan, Conn., that’s now a museum. It has a bulge in the middle to fit the punt, or depression, at the bottom of most wine bottles, making it look, ever so slightly, like the…

A Hot Honey to Elevate Your Meal

Red Clay, a company in Charleston, S.C., specializes in hot sauces, and just a trace of their new honey will elevate chicken — preferably fried, though grilled or roasted will do — with a touch of mellowness that has subtle bite. There’s more upfront heat, along with a vegetal note, in the company’s Barrel Aged…