peer review/experimental study/animals/cells Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells’ metabolism. These changes can be used as markers to discriminate whether a patient would…
Every year around 20 Australian children die from the incurable brain tumour, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years. There are no effective treatments, and almost all children die from the disease, usually within one year of diagnosis. A paper published today 12 Feb 2021 in…
Research over the last 20 years has shown that atherosclerosis is a chronic inflammatory condition of the arterial blood vessel wall. Soluble mediators such as cytokines and chemokines are pivotal players in this disease, promoting vascular inflammation. However, the development of anti-inflammatory therapeutics directed against such mediators that could prevent atherosclerosis has proven difficult, despite…
Many of the common preconditions to opening schools — including vaccines for teachers or students, and low rates of infection in the community — are not necessary to safely teach children in person, a consensus of pediatric infectious disease experts said in a new survey. Instead, the 175 experts — mostly pediatricians focused on public…
WASHINGTON — The Biden administration said Thursday it had secured 200 million more doses of coronavirus vaccines, enough to inoculate every American adult, but President Biden warned that logistical hurdles would most likely mean that many Americans will still not have been vaccinated by the end of the summer. The additional doses amount to a…
“Maria was a major contributor to the sea change in how cookbooks were done,” said Nach Waxman, founder of the Manhattan cookbook store Kitchen Arts and Letters and a colleague of Ms. Guarnaschelli’s at her first publishing job, as an editorial assistant at Harper & Row Publishers. She went on to hold senior positions at…
“Black is the renaissance of culture,” says Marcus Paul, one of the five Black creatives tapped by Sam Lobban, Nordstrom SVP Designer and New Concepts. Nordstrom honors Black culture and Black History Month through their newest pop-up shop, Concept 012: Black_Space. New Concepts is a platform that demonstrates Nordstrom’s commitment to bringing upcoming designers to…
For dreary days and weary souls, there is soup. Whether you’re stirred by brothy or blended varieties, those that lean creamy and rich or light and verdant, the perfect soup is out there for you. Find your match in at least one of the vegetarian recipes below. Sue Li describes this brothy number as “the…
We’re not accustomed to openly managing this trade-off in the United States, partly because of the power of health care interest groups, and perhaps because of a more individualistic culture. The New Washington Updated Feb. 11, 2021, 7:13 p.m. ET Not so in other countries. The vast majority of European nations, and many Asian ones,…
In recent years, scientists have figured out how to grow blobs of hundreds of thousands of live human neurons that look — and act — something like a brain. These so-called brain organoids have been used to study how brains develop into layers, how they begin to spontaneously make electrical waves and even how that…