Variable compensation and salesperson health

Researchers from University of Houston and University of Bochum published a new paper in the Journal of Marketing that examines how variable compensation plans for salespeople can lead to lower health. The study, forthcoming in the Journal of Marketing, is titled “Variable Compensation and Salesperson Health” and is authored by Johannes Habel, Sascha Alavi, and…

Virtual clinical trials could revolutionise the way new drugs are developed

New cutting-edge research undertaken at the University of Leicester could revolutionise the way new drugs are developed and the way patients are cared for, through a pioneering new approach using virtual clinical trials. Following a £500,000 Royal Academy of Engineering research funding award, Dr Himanshu Kaul, will expand research with his ‘virtual asthma patient’ to…

NIH-sponsored ACTIV-3 clinical trial closes enrollment into two sub-studies

The ACTIV-3 clinical trial, which is evaluating the safety and efficacy of investigational therapeutics for COVID-19 in hospitalized patients, has closed enrollment in two sub-studies: one examining the investigational monoclonal antibody therapy VIR-7831, and another evaluating the investigational combination monoclonal antibody therapy containing BRII-196 and BRII-198. The sub-studies were halted by the trial sponsor, the…

BCAS3-C16orf70 complex is a new actor on the mammalian autophagic machinery

Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria. PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged…

Molecular mechanisms identified in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens. These frequently occurring skin diseases are mostly attributed by biomedical scientists to a disturbed immune system, although the noticeable thickening and flaking of the epidermis, which is the outermost layer of…