Estrogen status – not sex – protects against heightened fear recall

Philadelphia, April 15, 2021 – A new study shows that markers of fear recall differ between men and women, but in a hormone-dependent manner. Aberrant fear-memory processing in the brain is thought to underlie anxiety disorders, which affect hundreds of millions of people worldwide. The neurobiological mechanisms underlying these disorders remain poorly understood, but recent…

Mathematical method builds synthetic hearts to identify how heart shape could be linked to disease

Researchers from King’s College London have created 3D replicas of full-sized healthy adult hearts from Computed Tomography (CT) images and analyzed how cardiac shape relates to function. Published today in PLOS Computational Biology, the study also includes 1000 new synthetic hearts that have been made open access allowing researchers to download and use them…

Genetic ancestry versus race can provide specific, targeted insights to predict and treat many diseases

The complex patterns of genetic ancestry uncovered from genomic data in health care systems can provide valuable insights into both genetic and environmental factors underlying many common and rare diseases–insights that are far more targeted and specific than those derived from traditional ethnic or racial labels like Hispanic or Black, according to a team of…