The three major drug distributors and a large drug manufacturer are closing in on a $26 billion deal with state and local governments that would end thousands of lawsuits over the companies’ role in the opioid epidemic, according to people close to the negotiations and new company filings. The deal is $4 billion more than…
We keep repeating: you are free to makeup however you like. If you follow the trends, you will probably want to know what can make your image somewhat provincial (from the point of view of modern fashionistas). So, what makeup is no longer fashionable? Graphic eyebrows In modern realities and the constant lack of time,…
ImageA dentist at work in Manhattan in June. Dentists and other providers of medical care have had to increase their spending on personal protective gear; some have sought to pass these costs on to patients.Credit…Brittainy Newman for The New York Times The New York Times is investigating the costs associated with testing and treatment for…
In the United States, the standard approach to distributing a routine vaccine is based on the assumption that there will be plenty of doses available. Ideally, everyone will then follow their doctors’ recommendations when it comes to being immunized against the germ in question. As a practical matter, though, rarely are both of those conditions…
TUCSON, Ariz., November 5, 2020 — The Pediatric IBD Foundation, ImproveCareNow, and the Critical Path Institute (C-Path) are proud to announce a collaboration establishing the Children’s Registry for the Advancement of Therapeutics (CREATE™). CREATE™ is a drug-agnostic safety registry designed to support the completion of global post-marketing safety requirements, as well as collect safety information…
NEW YORK, NY (Nov. 5, 2020)–Children and adults produce different types and amounts of antibodies in response to infection with the new coronavirus, SARS-CoV-2, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found. The differences in antibodies suggest the course of the infection and immune response is distinct…
Fossil fuel burning accounts for the majority of global greenhouse gas emissions, and to the world’s credit, several countries are working to reduce their use and the heat-trapping emissions that ensue. The goal is to keep global temperatures under a 1.5° to 2°C increase above preindustrial levels — the upper limits of the Paris Climate…
Researchers have designed a protein “decoy” that mimics the interface where the SARS-CoV-2 spike protein binds a human cell, one version of which could neutralize virus infection in cells and protect hamsters from viral challenge. The SARS-CoV-2 virus enters human cells when the spike protein binds to the human ACE2 receptor. While neutralizing antibodies to…
Two separate studies have identified nanobodies – which could be produced less expensively than monoclonal antibodies – that bind tightly to the SARS-CoV-2 spike protein and efficiently neutralize SARS-CoV-2 in cells. “The combined stability, potency, and diverse epitope engagement of our … nanobodies … provide a unique potential prophylactic and therapeutic strategy to limit the…
PITTSBURGH, Nov. 5, 2020 – Today in Science, researchers at the University of Pittsburgh School of Medicine describe a new method to extract tiny but extremely powerful SARS-CoV-2 antibody fragments from llamas, which could be fashioned into inhalable therapeutics with the potential to prevent and treat COVID-19. These special llama antibodies, called “nanobodies,” are much…