Q. What is a fecal transplant, and why would I want one? A. Fecal transplant is a medical procedure in which stool from a healthy donor is introduced into the intestine of a patient as a treatment for a disease. The idea is that the stool from the donor contains a healthful mix of gut…
Cambridge researchers have discovered the placenta regulates how much oxygen and nutrients it transports to babies during challenging pregnancies in a study using mice to model conditions in the womb. The placenta is the least understood organ and is notoriously difficult to study in pregnant women. But its ability to function properly is vital as…
IMAGE: The presence of more bacteria producing the tyrosine decarboxylase (TDC) enzyme means less levodopa in the bloodstream. view more Credit: S. El Aidy, University of Groningen Patients with Parkinson’s disease are treated with levodopa, which is converted into dopamine, a neurotransmitter in the brain. In a study published on 18 January in the journal Nature…
IMAGE: This is a schematic image showing the ETP expression and survival rate in liver tissue from HCC patients. view more Credit: UNIST Chronic liver disease is known as the silent killer, as it shows no obvious symptoms until the disease has progressed to an advanced stage. Therefore, making a proper diagnosis in the early stage…
IMAGE: (Left) Arabidopsis wild-type 9-day growth. (Center and right) The expression of lateral root founder cell marker the DR5 marker gene (DR5:Luciferase) in the root. White arrows show highly active DR5…. view more Credit: Kobe University How do plants space out their roots? A Japanese research team has identified a peptide and its receptor that help…
IMAGE: A 93-series chemical compound joins with a neuron’s NMDA receptor. Compounds like this have a high affinity for the receptor due to a unique motif that is drawn into a… view more Credit: Furukawa Lab/CSHL Cold Spring Harbor, NY — The ideal drug is one that only affects the exact cells and neurons it is…
IMAGE: Firsthand accounts with young adults who use drugs find rapid-acting fentanyl test strips are an effective tool to reduce overdose risk. view more PROVIDENCE, R.I. [Brown University] — Fentanyl is a synthetic opioid so potent that a miniscule amount equivalent to several grains of saltcan cause afataloverdose. Yet it’s difficult for people who use drugs…
The Icahn School of Medicine at Mount Sinai has entered into two exclusive licenses to develop the drug pentosan polysulfate sodium for the treatment of mucopolysaccharidosis (MPS), with Australia-based company Paradigm Biopharmaceuticals Ltd. (ASX: PAR) and ReqMed Company, Ltd. of Japan. MPS is a group of 11 lysosomal storage diseases, metabolic disorders caused by genetic…
IMAGE: An example of bone sections used to study responses to mechanical loading. view more Credit: School of Health and Human Sciences INDIANAPOLIS — A $2.85 million National Institute of Arthritis and Musculoskeletal and Skin Diseases-funded study at IUPUI will advance understanding of how bone cells sense and respond to mechanical force, one of the cues…
ANN ARBOR, Mich.- Sleeping more than nine hours per night during pregnancy may be associated with late stillbirth, a new Michigan Medicine-led international study suggests. Researchers analyzed online surveys involving 153 women who had experienced a late stillbirth (on or after 28 weeks of pregnancy) within the previous month and 480 women with an ongoing…